Master Modules Translational Neuroscience

Module 1 Neuroanatomy and Neurophysiology

undefinedProf. Dr. med. Katrin Amunts       undefinedBrain Research
General principles in neuroanatomy and neurophysiology, sensory and motoric systems and integrative components of the nervous system will highlight the relevance for clinical neurology. The practical course in neuroanatomy concentrates on gross anatomy and histology of the human brain and spinal cord.   undefinedmore...

Module 2a Foundations of Medical Physics

Earth-Magnetic-MRI from Magritek LTD, New Zealand

undefinedProf. Dr. T. Heinzel     undefinedPhysics
Upon completion of this course, students should be able to describe physics concepts with relevance in medicine and apply these concepts in diagnostics and therapy. After the attendance of this course, students are capable to operate essential medical physics equipment and understand their physics and document and analyse the scientific experiments. undefinedmore...

Module 2b High-Throughput Analysis: Genomics, Proteomics and Data Analysis

undefinedProf. Dr. K. Köhrer          undefinedGenomics and Transcriptomics
The students will learn to describe the various gene regulation mechanisms on the DNA and RNA level and all necessary analytical tools to analyse genes, genomes, and gene expression, to apply state-of-the-art proteomic approach facilitating protein mass spectrometry (MS) and to describe the function of MS. In the data analysis part the students will be taught to analyse genomic and proteomic data generated by high-throughput procedures.     undefinedmore...

Module 3a Basic Concepts and Techniques of Molecular Neurobiology

undefinedProf. Dr. H.-W. Müller        undefinedMolecular Neurobiology
After attending this course students are able to formulate and explain basic principles of molecular and cellular neuroscience. They can apply the basic neurocytological methodologies for creating, differentiating and characterising primary nerve cell cultures and evaluate and assess the results. Students are capable of carrying out nervous tissue preparation.  undefinedmore...

Module 3b Cellular and Molecular Analyses of Brain Development

undefinedProf. Dr. C. R. Rose   undefinedNeurobiology
The students are taught to describe and apply the fundamental concepts and techniques of fluorescence-based immunohistochemistry. They can use these concepts for the identification of various cell types and brain structures and make judgements regarding physiological and development-related questions. Students can use advanced techniques in light and fluorescence microscopy.  undefinedmore...

Module 3c Cognitive Neuroscience

undefinedProf. Dr. S. B. Eickhoff   undefinedNeuropsych. Systems Biology
Students are taught to describe the functioning of the human brain with respect to processes such as neural rhythms and oscillatory networks as well as systems such as control of movement, perception and emotions. They will learn to explain and interpret modern imaging methods for representing the structures and functions of the human brain as well as methods for brain stimulation.  undefinedmore...

Module 3d Protein Pathology in Neurodegenerative Diseases and Mental Brain Disorders

undefinedProf. Dr. S. Weggen                                                                    undefinedNeuropathology
After completion of this module students will have a solid understanding of two of the most common and devastating brain diseases, the neurodegenerative disorder Alzheimer’s disease and the mental illness schizophrenia.  undefinedmore...

Module 4a Experimental and Translational Neuroimaging

undefinedDr. D. Elmenhorst    undefinedMolecular Neuroimaging
Upon completion of this module the students are capable to describe how neuroscientific questions can be adequately addressed by neuroimaging techniques and to identify the appropriate imaging technique for a specific question. The students will be able to apply commonly used neuroimaging techniques in biomedical research with regard to human and animal studies.    undefinedmore...

Module 4b Methods in Neurosciences

undefinedProf. Dr. O. Sergeeva       undefinedMolecular Neurophysiology
The students will learn to describe the general principles in selected methods of locomotor and sensory tests for rodents, the cellular composition of the central nervous system with strong emphasis of developmental changes, cellular function and species differences addressing model species such as mouse and rat, and the principles of electrophysiological recordings (patch-clamp) from ex-vivo brain slices and cultured neurons.   undefinedmore...

Module 4c Non-Mammalian Model Systems of Neurodegenerative Diseases

undefinedProf. Dr. A. von Mikecz    undefined Cell Biology
The students will learn to describe the development of the nervous system in non-mammalian animal models, to delineate model systems for neurodegenerative diseases in nematodes and flies and evaluate their contribution to the elucidation of respective pathomechanisms in humans.         undefinedmore...

Module 5a Neuroimmunology

undefinedProf. Dr. O. Aktas     undefinedMolecular Neurology
After completion of this module the students are able to describe the immune system and its relevance to physiological and pathological conditions of the nervous system. They are capable to hypothesize on possible mechanisms involved in the development of neurological diseases and possible immunological therapy approaches.  undefinedmore...

Module 5b Animal Models of Human Diseases

undefinedProf. Dr. U. Rüther  undefinedMolecular Development of Mammals
The participants acquire knowledge regarding the basic concepts of vertebrate development. The students will understand and be able to apply standard molecular, immunocytochemical and physiological experimental techniques and develop relevant experimental designs for given scientific questions. undefinedmore...

Module 5c Systems Neuroscience

undefinedProf. Dr. O. A. Sergeeva      undefinedMolecular Neurophysiology
The students are able to describe how behavioural states are organized on systemic, network-, cellular and molecular levels in relation to the daily circle. This includes sleep and waking, energy administration (temperature regulation, food intake and metabolism), and the release of hypothalamic hormones. The pathophysiology of these functions includes sleep disorders (e.g. narcolepsy, sleep apnoea), anorexia, obesity, central aspects of diabetes mellitus.  undefinedmore....

Module 6 Research Ethics and Technics

undefinedProf. Dr. Heiner Fangerau
Upon completion of the research ethics part the students will be able to describe the basics in philosophy of science, theoretical and historical foundations of neuroscience, models of reasoning in biomedical ethics and research ethics, with a special focus on research on humans. The research technics part is a lab rotation in different laboratories.   undefinedmore...

Module Pilot Project

The Pilot Project serves to illustrate research activities in a working group on a given experimental project. Students perform a 12-week placement in a working group. They are assigned to a specific experimental project on which they can work under one-to-one supervision. The ability of adequately reporting scientific results is supported by an accompanying seminar in scientific writing and presenting.    undefinedmore...

Module Project Proposal

The project proposal serves as a preparatory exercise for the Masters thesis. Students perform a 12-week placement in a working group on an experimental project of their choice. After completion a project sketch for the Masters thesis is to be drawn up. Accompanying lectures and practicals in statistical analysis of high-dimensional data support the ability of the students to analyse their data gathered.     undefinedmore...

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